Dab tsi yog Sparger hauv Fermenter?
Hauv luv luv, ASparger hauv Fermenteryog ib qho cuab yeej siv los qhia cov cua lossis lwm yam roj rau hauv lub nkoj Fermentation.
Nws feem ntau yog cov yeeb nkab perforated nyob rau hauv qab ntawm lub nkoj los yog ze ntawm lub impeller thiab tso cai rau cov roj tso rau hauv cov kua los ntawm qhov me me los yog dav hlau.
Lub hom phiajntawm sparger yog muab cov pa oxygen rau cov txheej txheem aerobic fermentation lossis sib tov carbon dioxide (co2) rau cov txheej txheem anaerobic fermentation. lub sparger pab tswj kom muaj kev pom zoo ntawm cov pa oxygen hauv cov kab lis kev cai nruab nrab, uas yog qhov tseem ceeb rau kev loj hlob thiab cov metabolism hauv cov kab mob, xws li cov poov xab lossis cov kab mob.
Thaum lub sij hawm fermentation txheej txheem, lub sparger kuj yuav siv tau los tswj cov PH, kub thiab sib tov ntawm lub nkoj txheem. Nws yog feem ntau siv nyob rau hauv industrial-scale bioprocessing, qhov twg loj ntim ntawm cov kab mob yog kab lis kev cai ib txhij, kom ntseeg tau tias zoo ib yam thiab npaum fermentation.
Hauv thaj chaw fermentation, spargers ua lub luag haujlwm tseem ceeb hauv kev tsim qhov chaw zoo rau kev loj hlob microbial. Hauv cov ntsiab lus yooj yim, sparger yog cov cuab yeej siv los qhia cov pa roj (feem ntau yog cov pa oxygen lossis carbon dioxide) rau hauv cov kua nruab nrab. Thaum lub sij hawm fermentation, spargers feem ntau yog siv los tswj cov concentration ntawm yaj oxygen, uas yog ib qho tseem ceeb rau kev loj hlob ntawm microbial. Nyob rau hauv no blog ncej, peb mam li sib tham nyob rau hauv kom meej seb ib tug kis tau tus mob, nws ua haujlwm li cas, thiab nws qhov tseem ceeb nyob rau hauv cov txheej txheem fermentation.
Injector yog dab tsi?
Lub sparger yog ib qho cuab yeej siv los qhia cov pa roj (feem ntau yog cov pa oxygen lossis carbon dioxide) rau hauv cov kua nruab nrab. Distributors feem ntau muaj cov roj inlet thiab cov khoom ntxeem tau los faib cov pa rau hauv cov kua. Cov ntaub ntawv ntxeem tau tuaj yeem tsim los ntawm ntau yam ntaub ntawv xws li sintered hlau, ceramics lossis polymers.
Spargers feem ntau yog siv los tswj cov concentration ntawm cov pa oxygen hauv cov kua dej thaum lub sij hawm fermentation. Qhov no yog vim hais tias cov pa oxygen yog ib qho tseem ceeb rau kev loj hlob ntawm cov kab mob microbial thiab nws muaj zog cuam tshuam rau kev ceev thiab efficiency ntawm fermentation. Tsis tas li ntawd, eductors tuaj yeem siv los tswj cov pH ntawm qhov nruab nrab fermentation los ntawm kev qhia cov pa roj carbon dioxide lossis lwm cov kua qaub.
Hom ntawm distributor:
Muaj ntau ntau hom kev sib kis feem ntau siv hauv kev lag luam fermentation, txhua tus muaj nws tus kheej zoo thiab qhov tsis zoo. Feem ntau hom kab mob kis tau yog:
1. Porous Distributors:
Cov distributors no yog ua los ntawm cov ntaub ntawv ntxeem tau xws li sintered hlau, ceramics los yog polymers. Lawv feem ntau siv hauv kev lag luam vim lawv cov kev ua haujlwm siab thiab kev siv yooj yim.
2. Bubble injectors:
Cov injectors no qhia cov roj rau hauv qhov nruab nrab fermentation hauv daim ntawv ntawm npuas. Lawv tsis tshua muaj txiaj ntsig ntau dua li cov porous spargers, tab sis feem ntau yog siv rau me me fermentations.
3. Membrane spargers:
Cov spargers siv cov roj permeable membrane los qhia cov roj rau hauv nruab nrab fermentation. Lawv ua haujlwm tau zoo, tab sis nyuaj dua los ntxuav thiab tu.
Qhov tseem ceeb ntawm spargers hauv fermenters:
Spargers ua lub luag haujlwm tseem ceeb hauv cov txheej txheem fermentation los ntawm kev tswj cov pa oxygen concentration thiab pH hauv nruab nrab fermentation. Qhov concentration ntawm yaj oxygen yog qhov tseem ceeb rau kev loj hlob ntawm microbial vim nws cuam tshuam rau tus nqi thiab kev ua haujlwm ntawm fermentation. Los ntawm kev tswj cov concentration ntawm cov pa oxygen, spargers tuaj yeem pab xyuas kom meej tias cov txheej txheem fermentation yog optimized rau ntau tshaj tawm los thiab zoo.
Ntxiv nrog rau kev tswj cov concentration ntawm cov pa oxygen, nebulizers tuaj yeem siv los tswj cov pH ntawm qhov nruab nrab fermentation. Qhov no tseem ceeb heev vim tias pH cuam tshuam rau tus nqi thiab kev ua haujlwm ntawm microbial kev loj hlob. Los ntawm kev qhia cov pa roj carbon dioxide xws li carbon dioxide, spargers tuaj yeem pab tswj hwm qhov pH zoo rau kev loj hlob ntawm microbial.
Cov laj thawj uas yuav tsum tau xav txog thaum xaiv tus kis kab mob:
Thaum xaiv ib qho sparger rau ib lub fermenter, ntau yam yuav tsum tau xav txog, nrog rau hom kab mob uas yog kab lis kev cai, qhov loj ntawm fermenter, thiab qhov xav tau fermentation tej yam kev mob. Piv txwv li, cov porous spargers feem ntau zoo dua rau cov fermentations loj vim lawv cov kev ua haujlwm siab, thaum huab cua npuas spargers yuav zoo dua rau cov me me fermentations. Qhov kev xaiv ntawm sparger tuaj yeem nyob ntawm seb cov kev cai tshwj xeeb ntawm cov txheej txheem fermentation, xws li qhov xav tau cov pa oxygen concentration lossis qhov zoo tshaj pH ntau.
Spreader Maintenance thiab Cleaning:
Kev tu thiab tu kom zoo yog qhov tseem ceeb los xyuas kom meej qhov ua tau zoo thiab tiv thaiv kev sib kis. Spargers yuav tsum tau ntxuav ib ntus kom tshem tawm cov kev tsim ntawm microbial kev loj hlob lossis lwm yam kab mob uas yuav cuam tshuam rau lawv cov kev ua haujlwm. Cov txheej txheem ntxuav tej zaum yuav txawv nyob ntawm seb hom sparger, tab sis feem ntau cuam tshuam nrog kev ntub cov sparger hauv cov tshuaj ntxuav, tom qab ntawd yaug nrog dej. Ntxiv nrog rau kev tu tsis tu ncua, lub sparger yuav tsum tau tshuaj xyuas tsis tu ncua rau kev puas tsuaj lossis hnav thiab hloov raws li qhov tsim nyog.
Hom spargers siv nyob rau hauv fermenters
1. Porous Distributor:
Porous spargers yog tsim los ntawm ntau yam ntaub ntawv xws li sintered hlau, ceramics thiab polymers. Cov spargers no muaj thaj chaw siab thiab ntau qhov me me, uas tso cai rau cov roj sib npaug sib npaug thoob plaws hauv nruab nrab fermentation. Kev ua haujlwm siab ntawm cov porous spargers ua rau lawv yog qhov kev xaiv nrov rau cov fermentations loj, qhov twg cov roj kis tau zoo yog qhov tseem ceeb rau kev pom kev loj hlob ntawm microbial. Porous spargers kuj muaj qhov zoo ntawm kev yooj yim los ntxuav thiab tswj, vim lawv feem ntau yog tsim los rau disassembled thiab ntxuav ntawm cov khoom siv.
2. Npuas Shooter:
Bubble injectors, tseem hu ua diffusers, qhia roj rau hauv qhov nruab nrab fermentation hauv daim ntawv ntawm npuas. Cov spargers no feem ntau yog ua los ntawm cov khoom ntxeem tau los yog cov mesh zoo uas tsim cov npuas me me thaum cov roj nkag mus. Bubble injectors feem ntau yog siv rau me me fermentations qhov twg cov roj kis tau tus nqi siab tsis tseem ceeb. Bubble spargers muaj qhov zoo ntawm kev siv yooj yim thiab pheej yig, tab sis lawv yuav ua tau tsawg dua li cov porous spargers thiab tsim kom muaj kev kub ntxhov ntau hauv qhov nruab nrab fermentation.
3. Membrane distributor:
Membrane spargers siv cov pa roj permeable los qhia cov roj rau hauv nruab nrab fermentation. Cov spargers no muaj thaj chaw siab thiab ntau qhov me me, uas tso cai rau cov roj sib npaug sib npaug thoob plaws hauv nruab nrab fermentation. Membrane spargers yog qhov ua tau zoo thiab tuaj yeem hloov cov roj ntawm kev kub ceev, ua rau lawv muaj kev xaiv nrov rau cov fermentation loj. Membrane spargers, txawm li cas los xij, tuaj yeem nyuaj dua los ntxuav thiab tswj vim tias daim nyias nyias nyias nyias thiab yooj yim puas.
4. Nto Aerators:
Surface aerators, tseem hu ua agitators, tsim turbulent ntws ntawm qhov nruab nrab ntawm fermentation, tso cai rau cov pa nkag mus rau hauv cov kua. Cov distributors no feem ntau yog siv nyob rau hauv me me fermentations qhov twg cov roj kis tau tus nqi siab tsis tseem ceeb. Deg aerators muaj qhov zoo ntawm kev siv yooj yim thiab pheej yig, tab sis lawv yuav ua haujlwm tsawg dua li lwm hom spargers thiab tsim kom muaj kev kub ntxhov ntau hauv qhov nruab nrab fermentation.
5. Syringe:
Eductors siv lub dav hlau roj siab siab los ua kom muaj kev kub ntxhov hauv qhov nruab nrab fermentation, ua rau cov pa nkag mus rau hauv cov kua. Cov kab sib kis no feem ntau yog siv rau hauv me me fermentations thiab muaj qhov zoo ntawm kev siv yooj yim thiab pheej yig. Txawm li cas los xij, cov tshuaj txhaj tshuaj yuav ua haujlwm tsawg dua li lwm hom spargers thiab tsim kom muaj kev kub ntxhov ntau dua hauv qhov nruab nrab fermentation.
Xaiv tus kab mob kis tau zoo:
Thaum xaiv ib qho sparger rau lub fermenter, ntau yam yuav tsum tau xav txog, xws li hom kab mob kab mob, qhov loj ntawm lub fermenter, thiab qhov xav tau fermentation tej yam kev mob. Qhov kev xaiv ntawm sparger tuaj yeem nyob ntawm seb cov kev cai tshwj xeeb ntawm cov txheej txheem fermentation, xws li qhov xav tau cov pa oxygen concentration lossis qhov zoo tshaj pH ntau. Kev tu thiab tu kom zoo yog qhov tseem ceeb los xyuas kom meej qhov ua tau zoo thiab tiv thaiv kev sib kis. Los ntawm kev nkag siab txog ntau hom kev sib kis muaj thiab lawv qhov zoo thiab qhov tsis zoo, cov kws tshaj lij fermentation tuaj yeem txiav txim siab paub txog yuav ua li cas txhawm rau txhim kho cov txheej txheem fermentation thiab ua tiav cov txiaj ntsig xav tau.
Lub luag haujlwm tseem ceeb ntawm sparger hauv fermenter
1. Oxygenation:
Ib qho ntawm lub luag haujlwm tseem ceeb ntawm sparger hauv lub fermenter yog muab cov pa oxygen rau cov kab mob uas muaj kab mob. Qhov no tseem ceeb tshwj xeeb tshaj yog rau cov kab mob aerobic uas xav tau oxygen rau kev loj hlob thiab cov metabolism. Lub sparger xa cov pa oxygen mus rau qhov nruab nrab fermentation nyob rau hauv daim ntawv ntawm huab cua npuas los yog cua ntws, ua kom cov microbes nqus cov pa thiab siv nws rau lub zog tsim.
2. Mix:
Ntxiv nrog rau kev muab cov pa oxygen, lub sparger kuj tseem ua lub luag haujlwm tseem ceeb hauv kev sib xyaw cov fermentation nruab nrab. Thaum cov roj nkag mus rau hauv nruab nrab, nws tsim kev kub ntxhov, uas pab faib cov khoom noj thiab lwm yam khoom xyaw tseem ceeb sib npaug thoob plaws hauv cov kua. Kev sib xyaw kom zoo yog qhov tseem ceeb kom ntseeg tau tias kev loj hlob ntawm microbial zoo li nws tso cai rau cov kab mob kom tau txais cov as-ham uas lawv xav tau thiab tshem tawm cov khoom pov tseg.
3. PH Control:
Spargers tuaj yeem siv los tswj cov pH ntawm qhov nruab nrab fermentation los ntawm kev qhia cov pa roj carbon dioxide lossis lwm cov kua qaub rau hauv cov kua. Qhov no pab khaws cov pH nyob rau hauv qhov xav tau ntau yam thiab tiv thaiv kev loj hlob ntawm cov teeb meem microbes uas vam meej nyob rau hauv acidic ib puag ncig.
4. Kev tswj qhov kub thiab txias:
Qee zaum, spargers kuj tuaj yeem siv los tswj qhov kub ntawm qhov nruab nrab fermentation. Los ntawm kev qhia cov cua txias, lub sparger tuaj yeem pab txo qhov kub ntawm cov xov xwm thiab tiv thaiv overheating. Hloov pauv, cua sov tuaj yeem siv los ua kom qhov kub thiab txias ntawm qhov nruab nrab thiab txhawb kev loj hlob microbial.
5. Ua npuas ncauj tswj:
Thaum kawg, cov tshuaj tsuag kuj tuaj yeem siv los tswj kev ua npuas ncauj thaum fermentation. Ua npuas ncauj tuaj yeem yog ib qho teeb meem loj hauv fermentation vim nws cuam tshuam nrog cov txheej txheem sib xyaw thiab txo qhov ua tau zoo ntawm tus xa khoom. Los ntawm kev qhia airflow mus rau hauv nruab nrab fermentation, spargers tuaj yeem pab tawg ua npuas ncauj thiab tiv thaiv ua npuas ncauj.
hauv kev xaus:
Hauv cov ntsiab lus, spargers ua lub luag haujlwm tseem ceeb hauv cov txheej txheem fermentation los ntawm kev muab cov pa oxygen, sib xyaw fermentation media, tswj pH thiab kub, thiab tiv thaiv kev ua npuas ncauj. Xaiv qhov raug hom sparger thiab tswj thiab tu nws kom zoo yog qhov tseem ceeb rau kev ua kom cov txheej txheem fermentation thiab ua tiav cov txiaj ntsig xav tau. Los ntawm kev nkag siab txog kev ua haujlwm ntawm tus xa khoom hauv lub fermenter, cov kws tshaj lij fermentation tuaj yeem txiav txim siab paub yuav ua li cas txhawm rau txhim kho cov txheej txheem fermentation thiab ua tiav cov txiaj ntsig xav tau.
Kev siv cov distributor hauv fermenter
1. Qhuav npias thiab cawv:
Ib qho ntawm cov kev siv ntau tshaj plaws rau kev sib kis hauv fermenters yog hauv kev tsim npias thiab cawv. Nyob rau hauv cov kev lag luam no, spargers feem ntau yog siv los muab cov pa oxygen rau cov poov xab thaum lub sij hawm fermentation, uas pab txhawb kev noj qab haus huv poov xab loj hlob thiab muaj txiaj ntsig fermentation. Spargers kuj tseem siv tau los pab tswj qhov kub thiab pH ntawm qhov nruab nrab fermentation, uas yog qhov tseem ceeb rau kev ua tiav qhov xav tau tsw thiab qib cawv hauv cov khoom kawg.
2. Bioremediation:
Spargers kuj tseem siv rau hauv thaj chaw bioremediation, uas suav nrog kev siv cov kab mob sib kis los rhuav tshem cov pa phem thiab lwm yam kuab paug hauv ib puag ncig. Nyob rau hauv daim ntawv thov no, spargers yog siv los qhia cov pa oxygen rau hauv qhov chaw uas muaj kab mob, uas pab txhawb kev loj hlob ntawm cov kab mob hauv lub luag haujlwm rau kev rhuav tshem cov pa phem. Cov txheej txheem no tshwj xeeb tshaj yog siv rau kev ntxuav cov av thiab cov dej hauv av uas kis tau los ntawm cov khoom siv roj av, cov kuab tshuaj thiab lwm yam khoom siv tshuaj.
3. Kev tsim tshuaj:
Cov neeg xa khoom kuj tau siv dav hauv kev lag luam kws tshuaj rau kev tsim cov tshuaj tiv thaiv, tshuaj tua kab mob thiab lwm yam tshuaj. Hauv cov ntawv thov no, spargers yog siv los qhia cov pa oxygen rau hauv cov kab lis kev cai microbial lub luag haujlwm los tsim cov khoom xav tau. Spargers tseem tuaj yeem pab sib tov qhov nruab nrab fermentation thiab tswj qhov kub thiab pH ntawm kab lis kev cai, uas yog qhov tseem ceeb rau kev tswj hwm kev noj qab haus huv thiab kev tsim khoom ntawm microbial kab lis kev cai.
4. Muaj fermentation:
Spargers kuj tau siv dav hauv kev lag luam loj loj los tsim cov enzymes, amino acids, thiab lwm yam khoom siv roj ntsha. Hauv cov ntawv thov no, spargers yog siv los muab cov pa oxygen rau cov kab lis kev cai microbial thiab pab tswj qhov kub thiab pH xav tau los ntawm kab lis kev cai. Kev tsim nyog sparging yog qhov tseem ceeb rau kev ua tiav cov txiaj ntsig siab thiab tswj kev noj qab haus huv thiab tsim khoom ntawm kab lis kev cai microbial.
5. Kev Tshawb Fawb thiab Kev Txhim Kho:
Thaum kawg, cov kab mob kis tau feem ntau siv hauv kev tshawb fawb thiab kev tsim kho qhov chaw los kawm txog kev loj hlob thiab kev coj tus cwj pwm ntawm cov kab mob hauv ib cheeb tsam uas tswj tau. Spargers tuaj yeem siv los qhia ntau yam ntawm cov pa roj rau hauv fermentation media, tso cai rau cov kws tshawb fawb los kawm txog qhov cuam tshuam ntawm ib puag ncig sib txawv ntawm microbial kev loj hlob thiab cov metabolism.
hauv kev xaus
Hauv cov ntsiab lus, spargers yog ib feem tseem ceeb ntawm ntau cov txheej txheem fermentation, muab cov pa oxygen, sib xyaw fermentation media, thiab tswj qhov kub thiab pH ntawm kab lis kev cai. Kev siv cov khoom sib kis yog qhov tseem ceeb rau kev ua tiav cov txiaj ntsig siab thiab tswj kev noj qab haus huv thiab tsim khoom ntawm kab lis kev cai microbial. Los ntawm kev nkag siab txog ntau yam kev siv thiab kev siv cov khoom sib kis hauv fermentation, cov kws tshaj lij fermentation tuaj yeem txiav txim siab paub yuav ua li cas txhawm rau txhim kho cov txheej txheem fermentation thiab ua tiav cov txiaj ntsig xav tau.
Qhov twg yog Nrov Fermenter Sprayer?
nozzle sprayer hauv fermenter thiabOrifice distributors hauv fermenters
Nozzles thiab orifice distributors yog ob hom ntawm distributors siv nyob rau hauv fermenters. Nov yog cov ntaub ntawv ntau ntxiv ntawm txhua qhov:
1. Nozzle distributors hauv fermenters:
Lub nozzle sparger yog ib tug sparger uas siv ib tug series ntawm nozzles los qhia cov cua npuas rau hauv nruab nrab fermentation. Nozzles feem ntau yog teem nyob rau hauv ib daim phiaj qauv nyob rau hauv qab ntawm lub fermenter los ntawm uas cov pa yog nkag ntawm tus nqi tswj. Nozzle spargers yog nrov nyob rau hauv industrial-scale fermentations vim hais tias lawv muab kev sib xyaw kom zoo thiab oxygenation ntawm qhov nruab nrab fermentation. Lawv kuj yog ib qho yooj yim los ntxuav thiab tswj.
2. Orifice distributors hauv fermenters:
Ib qho orifice sparger yog ib qho sparger uas siv cov qhov me me los yog cov orifices los qhia cov pa npuas rau hauv nruab nrab fermentation. Cov orifices feem ntau yog teem rau hauv ib daim phiaj qauv nyob rau hauv qab ntawm lub fermenter los ntawm cov pa roj nkag ntawm tus nqi tswj. Orifice spargers yog qhov nrov hauv R & D ib puag ncig vim tias lawv tso cai rau kev tswj xyuas cov pa roj carbon monoxide thiab tuaj yeem siv los kawm txog cov txiaj ntsig ntawm cov roj sib txawv ntawm kev loj hlob ntawm microbial thiab cov metabolism.
Ob lub nozzles thiab orifice spargers muaj txiaj ntsig zoo hauv kev muab cov pa oxygen rau cov kab lis kev cai microbial thiab sib xyaw cov fermentation nruab nrab. Qhov kev xaiv ntawm sparger nyob ntawm seb cov kev cai tshwj xeeb ntawm cov txheej txheem fermentation, nrog rau qhov loj ntawm lub fermenter, hom kab mob kab mob, thiab qhov xav tau ntawm cov fermentation. Thaum kawg, lub hom phiaj yog xaiv cov sparger uas muab cov roj hloov pauv tau zoo thiab txhawb kev noj qab haus huv microbial loj hlob thaum txo qis ua npuas dej thiab lwm yam kev mob tshwm sim tsis zoo.
nyob rau hauv xaus:
Hauv cov ntsiab lus, sparger yog ib feem tseem ceeb ntawm cov txheej txheem fermentation thiab ua lub luag haujlwm tseem ceeb hauv kev tswj cov concentration ntawm cov pa oxygen thiab pH hauv nruab nrab fermentation. Xaiv hom kev sib kis kom raug thiab tswj xyuas thiab tu nws kom zoo tuaj yeem pab ua kom cov txheej txheem fermentation zoo tshaj plaws kom tau txais txiaj ntsig thiab zoo. Los ntawm kev nkag siab tias tus kab mob kis tau li cas thiab nws ua haujlwm li cas, cov kws tshaj lij fermentation tuaj yeem txiav txim siab paub txog yuav ua li cas txhawm rau txhim kho cov txheej txheem fermentation thiab ua tiav cov txiaj ntsig xav tau.
Koj puas xav ua kom zoo dua koj cov txheej txheem fermentation nrog cov khoom sib kis?
Yog tias muaj, tsis txhob yig los tshawb txog ntau yam kev xaiv nthuav dav kom pom tias lawv tuaj yeem tau txais txiaj ntsig li cas rau koj daim ntawv thov tshwj xeeb.
Hu rau tus kws tshaj lij fermentation thiab xaiv lossis OEM txoj cai sintered sparger hnub no kom paub ntau ntxiv thiab pib txhim kho koj cov txheej txheem fermentation!
Cov peev txheej ntxiv:
Rau cov neeg nyeem xav paub ntxiv txog cov neeg xa khoom hauv fermenters, muaj ntau yam kev pab. Qee cov ntaub ntawv pom zoo muaj xws li:
"Fermentation Microbiology thiab Biotechnology" los ntawm EMT El-Mansi, CFL Amaral thiab WWM Souza (2019)
"Principles of Bioprocess Engineering" los ntawm Pauline M. Doran (2012)
"Phau Ntawv Qhia Txog Kev Lag Luam Cell: Mammalian, Microbial, thiab Plant Cells" Editor-in-Chief Victor G. Aunins (2010)
Post lub sij hawm: May-05-2023
